Do Lubricants Affect Pregnancy Chances? Many couples wonder if lubricants can prevent conception. Oil based lubricants (like Vaseline, coconut oil, creams, lotions) can slow down sperm movement and reduce pregnancy chances. Pre Seed Fertility Friendly Personal Lubricant, 9 ct Kroger Is Coconut Lube a Safe and Effective Personal Lubricant Choice Conceive Plus Let's talk about lubricants and fertility. If you're TTC, the type of lube you use can either support or sabotage your chances of conceiving. Here's what research shows: All impact sperm in Oil based lube can cause some condom materials to break. Instead, use water based or silicone lube with condoms. Remember: Condoms do more than just help prevent pregnancy. Using condoms with new partners